BDBM50012825 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]azepino[3,2,1-hi]indole-2-carboxylic acid thiazol-2-ylamide::CHEMBL302838

SMILES O=C(Nc1nccs1)C1C(=O)N2c3c1cccc3CCc1ccccc21

InChI Key InChIKey=PJXDFVUCESIRMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012825   

LigandPNGBDBM50012825(CHEMBL302838 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]...)
Affinity DataIC50: 2.10E+4nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012825(CHEMBL302838 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]...)
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed