BDBM50012645 CHEMBL3261055

SMILES [H][C@]12CSC(N)=N[C@]1(CO[C@@H]2C(F)(F)F)c1cc(NC(=O)c2cnc(CF)cn2)ccc1F

InChI Key InChIKey=XHNXAPUTQFTIOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012645   

TargetBeta-secretase 1(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50012645(CHEMBL3261055)
Affinity DataIC50: 6nMAssay Description:Inhibition of BACE1 in Wistar rat primary neuronal cells assessed as inhibition of production of amyloid beta (1 to 42) after 3 days by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed