BDBM50012631 CHEMBL2396987

SMILES C[C@]1(CCSC(N)=N1)c1ccccc1

InChI Key InChIKey=JLGLPAHFIFVDIC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012631   

TargetBeta-secretase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50012631(CHEMBL2396987)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells expressing swedish mutant using mcaFRET peptide as substrate measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50012631(CHEMBL2396987)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant human BACE1 by 7-methoxycoumarin-4-yl-acetyl-based FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed