BDBM50012572 CHEMBL3260795

SMILES O=C1CC(CN1c1cnc2c(cccc2c1)N1CCNCC1)c1ccccc1

InChI Key InChIKey=GIQNFCNDIZCJAU-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50012572   

Target5-hydroxytryptamine receptor 6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50012572(CHEMBL3260795)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human 5-HT6 receptor assessed as inhibition of 5-HT-induced cAMP level treated for 10 mins prior to 5-HT challenge for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50012572(CHEMBL3260795)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human 5-HT6 receptor assessed as inhibition of 5-HT-induced cAMP level treated for 10 mins prior to 5-HT challenge for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50012572(CHEMBL3260795)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT6 receptor expressed in CHO-K1 cell membrane after 3 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50012572(CHEMBL3260795)
Affinity DataKi:  3.10E+3nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50012572(CHEMBL3260795)
Affinity DataKi: >3.00E+4nMAssay Description:Binding affinity to 5-HT2B receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50012572(CHEMBL3260795)
Affinity DataKi: >3.00E+4nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed