BDBM50012435 2-(4-Fluoro-phenyl)-5-phenyl-thiazol-4-ol::CHEMBL68429

SMILES Oc1nc(sc1-c1ccccc1)-c1ccc(F)cc1

InChI Key InChIKey=KUOOEYKNEXFFMB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012435   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012435(CHEMBL68429 | 2-(4-Fluoro-phenyl)-5-phenyl-thiazol...)
Affinity DataIC50: 470nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase (5-lo) in human whole blood (HWBL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012435(CHEMBL68429 | 2-(4-Fluoro-phenyl)-5-phenyl-thiazol...)
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-lipoxygenase (5-lo) in intact rat polymorphonuclear leukocyte RPMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012435(CHEMBL68429 | 2-(4-Fluoro-phenyl)-5-phenyl-thiazol...)
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-LO in rat RBL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed