BDBM50012365 11-{2-[4-(2-Chloro-ethyl)-piperazin-1-yl]-acetyl}-5,11-dihydro-benzo[e]pyrido[3,2-b][1,4]diazepin-6-one::CHEMBL67532

SMILES ClCCN1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc23)CC1

InChI Key InChIKey=RRPDKZUBFMKHQR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50012365   

LigandPNGBDBM50012365(CHEMBL67532 | 11-{2-[4-(2-Chloro-ethyl)-piperazin-...)
Affinity DataKi:  52nMAssay Description:Inhibition of binding of [3H]N-Methyl-scopolamine to Muscarinic acetylcholine receptor M1 of transfected A9L cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50012365(CHEMBL67532 | 11-{2-[4-(2-Chloro-ethyl)-piperazin-...)
Affinity DataKi:  78nMAssay Description:The compound was tested for the inhibition of binding of [3H]N-Methyl-scopolamine to Muscarinic acetylcholine receptor M3 of transfected A9L cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50012365(CHEMBL67532 | 11-{2-[4-(2-Chloro-ethyl)-piperazin-...)
Affinity DataKi:  130nMAssay Description:Inhibition of binding of [3H]N-Methyl-scopolamine to Muscarinic acetylcholine receptor M4 of NG108-15 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50012365(CHEMBL67532 | 11-{2-[4-(2-Chloro-ethyl)-piperazin-...)
Affinity DataKi:  210nMAssay Description:Inhibition of binding of [3H]N-Methyl-scopolamine to Muscarinic acetylcholine receptor M2 of rat heart tissue membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed