BDBM50012272 CHEMBL1088840

SMILES CCCCn1c2ccc(CO)cc2c2ccccc2c1=O

InChI Key InChIKey=UULXHXIRZISPDW-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50012272   

TargetNuclear receptor ROR-alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012272(CHEMBL1088840)
Affinity DataIC50: 2.00E+4nMAssay Description:Inverse agonist activity at human ROR-alpha1 expressed in HEK293 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetNuclear receptor ROR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012272(CHEMBL1088840)
Affinity DataIC50: 2.00E+4nMAssay Description:Inverse agonist activity at human ROR-beta expressed in HEK293 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012272(CHEMBL1088840)
Affinity DataIC50: 2.00E+4nMAssay Description:Inverse agonist activity at human ROR-gamma1 expressed in HEK293 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012272(CHEMBL1088840)
Affinity DataIC50: 8.60E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNPC intracellular cholesterol transporter 1(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012272(CHEMBL1088840)
Affinity DataEC50: >3.00E+4nMAssay Description:Chaperone activity at FLAG/GFP-tagged NPC1 I1061T mutant (unknown origin) expressed in HEK293 cells assessed as increase in localization of protein m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed