BDBM50012268 CHEMBL1765172

SMILES CCCCn1c2c(OC)cc(cc2c2ccccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=YZYLAPSMVPVKOG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50012268   

TargetNuclear receptor ROR-alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012268(CHEMBL1765172)
Affinity DataIC50: 1.00E+4nMAssay Description:Inverse agonist activity at human ROR-alpha1 expressed in HEK293 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetNuclear receptor ROR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012268(CHEMBL1765172)
Affinity DataIC50: 1.00E+4nMAssay Description:Inverse agonist activity at human ROR-beta expressed in HEK293 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012268(CHEMBL1765172)
Affinity DataIC50: 1.00E+4nMAssay Description:Inverse agonist activity at human ROR-gamma1 expressed in HEK293 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012268(CHEMBL1765172)
Affinity DataIC50: 560nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed