BDBM50012246 CHEMBL58153::N-(1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl)-2-[2-(morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-malonamic acid methyl ester

SMILES COC(=O)C(NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@H](O)CC(C)C

InChI Key InChIKey=IEWAGORIVPFRDB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50012246   

TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 36nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 36nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 0.280nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed