BDBM50012171 CHEMBL3264474

SMILES O=C([C@@H]1COc2cc(Oc3ccccc3)ccc2C1)c1ncc(o1)-c1ccccn1

InChI Key InChIKey=KTRKLISDHZZCIZ-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50012171   

TargetFatty-acid amide hydrolase 1(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012171(CHEMBL3264474)
Affinity DataIC50: 460nMAssay Description:Inhibition of mouse brain FAAH incubated for 10 mins prior to rhodamine-tagged fluorophosphonate addition measured after 10 mins by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012171(CHEMBL3264474)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse brain KIAA1363 incubated for 10 mins prior to rhodamine-tagged fluorophosphonate addition measured after 10 mins by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012171(CHEMBL3264474)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse brain MAGL incubated for 10 mins prior to rhodamine-tagged fluorophosphonate addition measured after 10 mins by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012171(CHEMBL3264474)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse brain ABHD6 incubated for 10 mins prior to rhodamine-tagged fluorophosphonate addition measured after 10 mins by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012171(CHEMBL3264474)
Affinity DataKi:  27nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli using [14C]oleamide as substrate assessed as oleic acid formation by Dixon plot anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed