BDBM50012105 CHEMBL3263667

SMILES Cc1ccccc1N1CCN(CC1)c1ccc(cc1NC(=O)c1coc(n1)C1CC1)C(=O)NCCCN1CCCC1=O

InChI Key InChIKey=BUGHVZIQXBALLZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012105   

TargetFollicle-stimulating hormone receptor(Human)
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50012105(CHEMBL3263667)
Affinity DataEC50:  9.90E+4nMAssay Description:Positive allosteric modulation of human FSH receptor expressed in CHO cells assessed as effect on FSH-induced cAMP accumulation after 1 hr by HTRF as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetFollicle-stimulating hormone receptor(Human)
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50012105(CHEMBL3263667)
Affinity DataEC50:  100nMAssay Description:Positive allosteric modulation of human FSHR expressed in rat granulocytes assessed as FSH-induced estradiol production after 72 hrs by radioimmunoss...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetFollicle-stimulating hormone receptor(Human)
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50012105(CHEMBL3263667)
Affinity DataEC50: <100nMAssay Description:Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed