BDBM50012049 2-({5-[Ethyl-(2-fluoromethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-thiophene-2-carbonyl}-amino)-pentanedioic acid::CHEMBL42357

SMILES CCN(Cc1ccc2nc(CF)[nH]c(=O)c2c1)c1ccc(s1)C(=O)N[C@H](CCC(O)=O)C(O)=O

InChI Key InChIKey=DYTNTUQBQDDICP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012049   

TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012049(CHEMBL42357 | 2-({5-[Ethyl-(2-fluoromethyl-4-oxo-3...)
Affinity DataIC50: 930nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed