BDBM50011942 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-methoxy-phenyl)-3H-quinazolin-4-one::CHEMBL37699

SMILES COc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O

InChI Key InChIKey=AAYKUORGNKPQCI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50011942   

TargetGastrin/cholecystokinin type B receptor(Mouse)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50011942(CHEMBL37699 | 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-...)
Affinity DataIC50: 38nMAssay Description:Inhibition of [125I]CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50011942(CHEMBL37699 | 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [125I]-labeled CCK-8 sulfate binding to Cholecystokinin type B receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50011942(CHEMBL37699 | 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-...)
Affinity DataIC50: 38nMAssay Description:Inhibition of [125I]CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50011942(CHEMBL37699 | 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-...)
Affinity DataIC50: 360nMAssay Description:Inhibition of [125I]-labeled CCK-8 sulfate binding to Cholecystokinin type B receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed