BDBM50011940 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-ethyl-phenyl)-3H-quinazolin-4-one::CHEMBL36436

SMILES CCc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O

InChI Key InChIKey=NCGSSSMQVCTNLU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011940   

TargetGastrin/cholecystokinin type B receptor(Mouse)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50011940(CHEMBL36436 | 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of [125I]CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50011940(CHEMBL36436 | 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of [125I]-labeled CCK-8 sulfate binding to Cholecystokinin type B receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50011940(CHEMBL36436 | 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-...)
Affinity DataIC50: 330nMAssay Description:Inhibition of [125I]-labeled CCK-8 sulfate binding to Cholecystokinin type B receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed