BDBM50011938 2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-thiophen-2-yl-ethyl ester::CHEMBL37081

SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2cccs2)cc1O

InChI Key InChIKey=KCGLTUBCAGZLHP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011938   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011938(CHEMBL37081 | 2-Cyano-3-(3,4-dihydroxy-phenyl)-acr...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011938(CHEMBL37081 | 2-Cyano-3-(3,4-dihydroxy-phenyl)-acr...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011938(CHEMBL37081 | 2-Cyano-3-(3,4-dihydroxy-phenyl)-acr...)
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed