BDBM50011825 1,3-Dipropyl-8-thiophen-3-yl-3,7-dihydro-purine-2,6-dione::CHEMBL34504

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccsc1

InChI Key InChIKey=WITRDKMTFSMTLT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50011825   

TargetAdenosine receptor A1(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50011825(CHEMBL34504 | 1,3-Dipropyl-8-thiophen-3-yl-3,7-dih...)
Affinity DataKi:  2nMAssay Description:Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]cyclohexyladenosine (CHA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50011825(CHEMBL34504 | 1,3-Dipropyl-8-thiophen-3-yl-3,7-dih...)
Affinity DataKi:  10nMAssay Description:Inhibition of 1 nM [3H]N-6-(phenylisopropyl)adenosine binding to A1 receptors in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50011825(CHEMBL34504 | 1,3-Dipropyl-8-thiophen-3-yl-3,7-dih...)
Affinity DataKi:  39nMAssay Description:Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50011825(CHEMBL34504 | 1,3-Dipropyl-8-thiophen-3-yl-3,7-dih...)
Affinity DataKi:  121nMAssay Description:Inhibition of binding of [3H]5'-(N-ethylcarbamoyl)-adenosine to adenosine A2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed