BDBM50011762 (1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza-bicyclo[3.1.0]hexane-2,4-dione::(1S,5R)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza-bicyclo[3.1.0]hexane-2,4-dione::1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza-bicyclo[3.1.0]hexane-2,4-dione::CHEMBL281947

SMILES Nc1ccc(cc1)C12CC1C(=O)N(CC1CCCCC1)C2=O

InChI Key InChIKey=WUHIUYRMTKSZGJ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50011762   

TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762(CHEMBL281947 | 1-(4-Amino-phenyl)-3-cyclohexylmeth...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of estrogen production in hamster ovarian tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762(CHEMBL281947 | 1-(4-Amino-phenyl)-3-cyclohexylmeth...)
Affinity DataIC50: 780nMAssay Description:In vitro inhibition of estrogen production in hamster ovarian tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762(CHEMBL281947 | 1-(4-Amino-phenyl)-3-cyclohexylmeth...)
Affinity DataIC50: 3.30E+5nMAssay Description:In vitro inhibition of aldosterone production in rat adrenal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762(CHEMBL281947 | 1-(4-Amino-phenyl)-3-cyclohexylmeth...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of cytochrome P450 19A1 AromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762(CHEMBL281947 | 1-(4-Amino-phenyl)-3-cyclohexylmeth...)
Affinity DataIC50: 3.40E+4nMAssay Description:In vitro inhibition of progesterone production in hamster ovarian tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762(CHEMBL281947 | 1-(4-Amino-phenyl)-3-cyclohexylmeth...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762(CHEMBL281947 | 1-(4-Amino-phenyl)-3-cyclohexylmeth...)
Affinity DataIC50: 3.30E+5nMAssay Description:In vitro inhibition of progesterone production in hamster ovarian tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762(CHEMBL281947 | 1-(4-Amino-phenyl)-3-cyclohexylmeth...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of cytochrome P450 19A1 AromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762(CHEMBL281947 | 1-(4-Amino-phenyl)-3-cyclohexylmeth...)
Affinity DataIC50: 3.40E+4nMAssay Description:In vitro inhibition of aldosterone production in rat adrenal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed