BDBM50011709 CHEMBL354056::{1-[1-(2-{1-[3-(Benzyl-benzyloxycarbonyl-amino)-propyl]-2-oxo-pyrrolidin-3-yl}-1-cyclohexylmethyl-2-hydroxy-ethylcarbamoyl)-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H]1CCN(CCCN(Cc2ccccc2)C(=O)OCc2ccccc2)C1=O

InChI Key InChIKey=KWDURXSIERPOJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011709   

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011709({1-[1-(2-{1-[3-(Benzyl-benzyloxycarbonyl-amino)-pr...)
Affinity DataIC50: 275nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed