BDBM50011653 2-{3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-prop-2-ynyl}-2H-isoquinolin-1-one::CHEMBL282883

SMILES Cc1nnc2CN=C(c3cc(sc3-n12)C#CCn1ccc2ccccc2c1=O)c1ccccc1Cl

InChI Key InChIKey=KZADDXIFBRMCJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011653   

TargetPlatelet-activating factor receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50011653(CHEMBL282883 | 2-{3-[4-(2-Chloro-phenyl)-9-methyl-...)
Affinity DataIC50: 1nMAssay Description:PAF-antagonist activity determined in dog platelets by PAF-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed