BDBM50011557 CHEMBL3262576::US9592235, Example 165::US9855269, Compound 8

SMILES Nc1ncnc2ccc(cc12)-c1ccc(cc1)C#N

InChI Key InChIKey=KTKDOVXJHXOAOF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011557   

LigandPNGBDBM50011557(CHEMBL3262576 | US9592235, Example 165 | US9855269...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
LigandPNGBDBM50011557(CHEMBL3262576 | US9592235, Example 165 | US9855269...)
Affinity DataIC50: 2.60E+3nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent

LigandPNGBDBM50011557(CHEMBL3262576 | US9592235, Example 165 | US9855269...)
Affinity DataIC50: 2.60E+3nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent