BDBM50011318 3-(4-Carboxy-4-{4-[(2,4-diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-butyrylamino)-benzoic acid::CHEMBL421973

SMILES Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)NC(CCC(=O)Nc3cccc(c3)C(O)=O)C(O)=O)cnc2n1

InChI Key InChIKey=VFZCSZMXEDWCGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011318   

TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011318(CHEMBL421973 | 3-(4-Carboxy-4-{4-[(2,4-diamino-pte...)
Affinity DataIC50: 32nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from human cells (WI-L2/M4).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed