BDBM50011250 CHEMBL3260341

SMILES COC(=O)Nc1ccc-2c(NC(=O)[C@H](C)CCC[C@@H](c3cc-2ccn3)n2ccc(cc2=O)-c2c(F)ccc(Cl)c2F)c1

InChI Key InChIKey=CXCGNTAXXPYSAK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011250   

TargetCoagulation factor XI(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011250(CHEMBL3260341)
Affinity DataKi:  0.110nMAssay Description:Inhibition of human coagulation factor 11a after 20 to 180 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011250(CHEMBL3260341)
Affinity DataKi:  1nMAssay Description:Inhibition of human plasma kallikrein using S-2302 as substrate at 37 degC after 20 to 180 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed