BDBM50010935 2-{4-[(4-Amino-pteridin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid::CHEMBL430797

SMILES Nc1ncnc2ncc(CNc3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)nc12

InChI Key InChIKey=ACWNWYYLDYBWEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010935   

TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50010935(CHEMBL430797 | 2-{4-[(4-Amino-pteridin-6-ylmethyl)...)
Affinity DataIC50: 1.90E+4nMAssay Description:Compound was tested for its inhibitory activity against dihydrofolate reductase (DHFR), isolated from MTX-resistant WI-L2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50010935(CHEMBL430797 | 2-{4-[(4-Amino-pteridin-6-ylmethyl)...)
Affinity DataIC50: 1.90E+4nMAssay Description:Compound was evaluated for Dihydrofolate Reductase (DHFR) inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed