BDBM50010931 2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-benzoylamino}-3-hydroxy-pentanedioic acid::CHEMBL73267

SMILES Nc1nc(N)c2nc(CCc3ccc(cc3)C(=O)NC(C(O)CC(O)=O)C(O)=O)cnc2n1

InChI Key InChIKey=AWTWWFPVTXYYSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010931   

TargetFolylpolyglutamate synthase, mitochondrial(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010931(CHEMBL73267 | 2-{4-[2-(2,4-Diamino-pteridin-6-yl)-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50010931(CHEMBL73267 | 2-{4-[2-(2,4-Diamino-pteridin-6-yl)-...)
Affinity DataIC50: 5.90nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed