BDBM50010844 CHEMBL316868::N-[4-(1-Hydroxy-2-{2-[4-(3H-imidazol-1-yl)-phenoxy]-ethylamino}-ethyl)-phenyl]-methanesulfonamide

SMILES CS(=O)(=O)Nc1ccc(cc1)C(O)CNCCOc1ccc(cc1)-n1ccnc1

InChI Key InChIKey=DBTRNVNGJVUGQX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010844   

TargetBeta-2 adrenergic receptor(Dog)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50010844(CHEMBL316868 | N-[4-(1-Hydroxy-2-{2-[4-(3H-imidazo...)
Affinity DataIC50: 5.70E+3nMAssay Description:Tested for Beta-2 adrenergic receptor selectivity in canine lung tissue in anesthetized dogsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50010844(CHEMBL316868 | N-[4-(1-Hydroxy-2-{2-[4-(3H-imidazo...)
Affinity DataIC50: 5.10E+3nMAssay Description:Tested for beta1-receptor selectivity in canine cardiac tissue in anesthetized dogsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Human)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50010844(CHEMBL316868 | N-[4-(1-Hydroxy-2-{2-[4-(3H-imidazo...)
Affinity DataIC50: 3.60E+3nMAssay Description:Tested for beta-receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized dogsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed