BDBM50010819 CHEMBL3264783

SMILES Cc1cccc(Oc2ccc(cc2Cl)C(=O)NC2CC(C)(C)NC(C)(C)C2)c1C#N

InChI Key InChIKey=XZFXFBHFNMTUKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010819   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010819(CHEMBL3264783)
Affinity DataIC50: 140nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed