BDBM50010784 CHEMBL81070::N,N'-Bis-(4-bromo-phenyl)-guanidine

SMILES NC(Nc1ccc(Br)cc1)=Nc1ccc(Br)cc1

InChI Key InChIKey=LRCORPJIFQHXPW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010784   

TargetSigma non-opioid intracellular receptor 1(Human)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010784(CHEMBL81070 | N,N'-Bis-(4-bromo-phenyl)-guanidine)
Affinity DataIC50: 33nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010784(CHEMBL81070 | N,N'-Bis-(4-bromo-phenyl)-guanidine)
Affinity DataIC50: 350nMAssay Description:In vitro inhibitory activity against [3H]- (+)-3-PPP binding to Sigma opioid receptor in guinea pig brain membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010784(CHEMBL81070 | N,N'-Bis-(4-bromo-phenyl)-guanidine)
Affinity DataIC50: 540nMAssay Description:In vitro inhibitory activity against [3H]DTG binding to Sigma opioid receptor in guinea pig brain membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed