BDBM50010711 (6aR,13bS )11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::CHEMBL56666::cis-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::cis-11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol

SMILES CN1CCc2cc(Cl)c(O)cc2[C@H]2[C@@H]1CCc1ccccc21

InChI Key InChIKey=DMJWENQHWZZWDF-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50010711   

TargetD(1A) dopamine receptor(Rat)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50010711(cis-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydr...)
Affinity DataKi:  474nMAssay Description:In vitro affinity of compound towards dopamine (D1) receptor was determined by measuring their ability to displace [3H]SCH-23,390 from rat striatal h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50010711(cis-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydr...)
Affinity DataKi:  513nMAssay Description:Inhibition of [3H]SCH-23390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010711(cis-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydr...)
Affinity DataKi:  531nMAssay Description:Binding affinity to displace [3H]-SCH- 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50010711(cis-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydr...)
Affinity DataKi:  9.07E+3nMAssay Description:Displacement of [3H]spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50010711(cis-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydr...)
Affinity DataKi:  9.07E+3nMAssay Description:Displacement of [3H]spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed