BDBM50010700 CHEMBL265824::H-Tyr-Gly-Gly-Phe-Cys-Arg-Arg-D-Ala-Arg-Pro-Cys-NH2

SMILES C[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=QXGFABTWRXRRJN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50010700   

TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50010700(CHEMBL265824 | H-Tyr-Gly-Gly-Phe-Cys-Arg-Arg-D-Ala...)
Affinity DataIC50: 19nMAssay Description:Binding affinity against Opioid receptor delta 1 in guinea pig brain homogenate using [3H]- DPDPE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50010700(CHEMBL265824 | H-Tyr-Gly-Gly-Phe-Cys-Arg-Arg-D-Ala...)
Affinity DataIC50: 0.391nMAssay Description:Binding affinity against Opioid receptor kappa 1 in guinea pig brain homogenate using [3H]- U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50010700(CHEMBL265824 | H-Tyr-Gly-Gly-Phe-Cys-Arg-Arg-D-Ala...)
Affinity DataIC50: 2.30nMAssay Description:Binding affinity against Opioid receptor mu 1 in guinea pig brain homogenate using [3H]- PL-17 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50010700(CHEMBL265824 | H-Tyr-Gly-Gly-Phe-Cys-Arg-Arg-D-Ala...)
Affinity DataIC50: 1.66E+3nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50010700(CHEMBL265824 | H-Tyr-Gly-Gly-Phe-Cys-Arg-Arg-D-Ala...)
Affinity DataIC50: 4.41E+3nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed