BDBM50010685 (+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine::(6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL43345::Dihydrexidine, DHX

SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@H]3c2cc1O

InChI Key InChIKey=BGOQGUHWXBGXJW-UHFFFAOYSA-N

Data  42 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 46 hits for monomerid = 50010685   

TargetD(1A) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro binding affinity against Dopamine receptor D1 from rat striatal membrane using [125I]-SCH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]- #NAME from binding Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effective concentration was determined for the adenylate cyclase activity in rat striatal tissue as a measure of Dopamine receptor D1 functional acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMed
TargetD1 dopamine receptor(Crab-eating macaque)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi:  20.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi:  43.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi:  50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi:  230nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetGlycine amidinotransferase, mitochondrial(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetBeta-nerve growth factor(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetNorepinephrine transporter(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
Target5'-nucleotidase(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 8(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetSomatostatin(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetProtachykinin-1(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetProtachykinin-1(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetVIP peptides(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetGlycine amidinotransferase, mitochondrial(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetInterleukin-18(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetChloride channel protein 1(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetAdenosine kinase(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetAdenylate cyclase type 3(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetNatriuretic peptides A(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetAngiotensinogen(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetArginine vasopressin-induced protein 1(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetBombesin receptor subtype-3(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetCholecystokinin receptor type A(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetCholecystokinin receptor type A(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetPro-epidermal growth factor(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetGlutamate receptor 3(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of North Carolina

Curated by PDSP Ki Database
LigandPNGBDBM50010685((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed