BDBM50010684 (6aR,12bS)-6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL299161::N-n-propyldihydrexidine, N-Pr-DHX

SMILES CCCN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21

InChI Key InChIKey=VNVHTKVGILYCGH-UHFFFAOYSA-N

Data  4 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50010684   

TargetAdenylate cyclase type 5(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010684(N-n-propyldihydrexidine, N-Pr-DHX | CHEMBL299161 |...)
Affinity DataEC50: >10nMAssay Description:Effective concentration as Adenylate cyclase activity was measured in rat homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50010684(N-n-propyldihydrexidine, N-Pr-DHX | CHEMBL299161 |...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration was determined for the adenylate cyclase activity in rat striatal tissue as a measure of Dopamine receptor D1 functional acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50010684(N-n-propyldihydrexidine, N-Pr-DHX | CHEMBL299161 |...)
Affinity DataIC50: 651nMAssay Description:Displacement of [3H]- #NAME from binding Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010684(N-n-propyldihydrexidine, N-Pr-DHX | CHEMBL299161 |...)
Affinity DataIC50: 53nMAssay Description:Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010684(N-n-propyldihydrexidine, N-Pr-DHX | CHEMBL299161 |...)
Affinity DataKi:  6.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010684(N-n-propyldihydrexidine, N-Pr-DHX | CHEMBL299161 |...)
Affinity DataKi:  20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50010684(N-n-propyldihydrexidine, N-Pr-DHX | CHEMBL299161 |...)
Affinity DataKi:  320nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of North Carolina At Chapel Hill

Curated by PDSP Ki Database
LigandPNGBDBM50010684(N-n-propyldihydrexidine, N-Pr-DHX | CHEMBL299161 |...)
Affinity DataKi:  2.11E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMed