BDBM50010657 CHEMBL3264746

SMILES [H][C@]12O[C@]34CC[C@@]5(OCOc6c(O)ccc7C[C@@]3([H])N(CCc3ccccc3)CC[C@]4(c67)[C@]15[H])N(Cc1ccccc1)C2=O

InChI Key

Data  3 KI  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50010657   

TargetMu-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50010657(CHEMBL3264746)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50010657(CHEMBL3264746)
Affinity DataEC50:  9.20nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50010657(CHEMBL3264746)
Affinity DataEC50:  639nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells by CellKey methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50010657(CHEMBL3264746)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human delta opioid receptor expressed in HEK293 cells by CellKey methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50010657(CHEMBL3264746)
Affinity DataEC50:  1.25E+4nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells by CellKey methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50010657(CHEMBL3264746)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50010657(CHEMBL3264746)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50010657(CHEMBL3264746)
Affinity DataKi:  588nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed