BDBM50010621 6-[Propyl-(2-thiophen-3-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL7806

SMILES CCCN(CCc1ccsc1)C1CCc2c(O)cccc2C1

InChI Key InChIKey=RHRKSVACMIQFDY-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50010621   

TargetD(2) dopamine receptor(Rat)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50010621(CHEMBL7806 | 6-[Propyl-(2-thiophen-3-yl-ethyl)-ami...)
Affinity DataIC50: 8.80nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50010621(CHEMBL7806 | 6-[Propyl-(2-thiophen-3-yl-ethyl)-ami...)
Affinity DataIC50: 0.620nMAssay Description:In vitro inhibition of [3H]N-0437 binding to Dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50010621(CHEMBL7806 | 6-[Propyl-(2-thiophen-3-yl-ethyl)-ami...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50010621(CHEMBL7806 | 6-[Propyl-(2-thiophen-3-yl-ethyl)-ami...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50010621(CHEMBL7806 | 6-[Propyl-(2-thiophen-3-yl-ethyl)-ami...)
Affinity DataKi:  24nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D2L of CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50010621(CHEMBL7806 | 6-[Propyl-(2-thiophen-3-yl-ethyl)-ami...)
Affinity DataKi:  72nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D4.2 of CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed