BDBM50010468 CHEMBL3263997

SMILES CNS(=O)(=O)Nc1cncc(Cc2c(C)c3ccc(OC(=O)N(C)C)cc3oc2=O)c1

InChI Key InChIKey=NOZUCNQJIWADAC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010468   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50010468(CHEMBL3263997)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of truncated active C-Raf (unknown origin) assessed as MEK1 phosphorylation using inactive MEK1 K97R as substrate after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed