BDBM50010335 CHEMBL3263577

SMILES OCc1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1

InChI Key InChIKey=GICNKPZHUCVFNM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50010335   

TargetMonoacylglycerol lipase ABHD6(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010335(CHEMBL3263577)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010335(CHEMBL3263577)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010335(CHEMBL3263577)
Affinity DataIC50: 0.240nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010335(CHEMBL3263577)
Affinity DataIC50: 0.200nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed