BDBM50010282 2,7-difluorospiro[9H-fluorene-9,3'-(tetrahydro-1'H-pyrrole)]-2',5'-dione::CHEMBL418832

SMILES Fc1ccc2-c3ccc(F)cc3C3(CC(=O)NC3=O)c2c1

InChI Key InChIKey=GQKBFUUCXZFQNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010282   

TargetAldo-keto reductase family 1 member B1(Rat)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50010282(CHEMBL418832 | 2,7-difluorospiro[9H-fluorene-9,3'-...)
Affinity DataIC50: 9nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50010282(CHEMBL418832 | 2,7-difluorospiro[9H-fluorene-9,3'-...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed