BDBM50010274 Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(2-amino-ethylcarbamoyloxy)-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyl-dodecahydro-benzo[f]chromen-5-yl ester::Acetic acid 6-(2-amino-ethylcarbamoyloxy)-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyl-dodecahydro-benzo[f]chromen-5-yl ester::CHEMBL328561

SMILES CC(=O)O[C@H]1[C@@H](OC(=O)NCCN)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C

InChI Key InChIKey=FEXQCCZGFPBLFT-UHFFFAOYSA-N

Data  1 IC50  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50010274   

TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010274(CHEMBL328561 | Acetic acid (3R,4aR,5S,6S,6aS,10S,1...)
Affinity DataKd: >1.00E+5nMAssay Description:Inhibition of [125I]7-IHPP-Fsk binding to glucose transporter of human erythrocyte membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010274(CHEMBL328561 | Acetic acid (3R,4aR,5S,6S,6aS,10S,1...)
Affinity DataKd:  34nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010274(CHEMBL328561 | Acetic acid (3R,4aR,5S,6S,6aS,10S,1...)
Affinity DataIC50: 31nMAssay Description:Inhibition of [125 I]6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010274(CHEMBL328561 | Acetic acid (3R,4aR,5S,6S,6aS,10S,1...)
Affinity DataEC50:  600nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed