BDBM50009702 2-Chloro-9-methyl-9H-purin-6-ylamine::CHEMBL317398

SMILES Cn1cnc2c(N)nc(Cl)nc12

InChI Key InChIKey=XBMKMJLOOAHOKH-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50009702   

TargetCyclin-dependent kinase 1(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50009702(CHEMBL317398 | 2-Chloro-9-methyl-9H-purin-6-ylamin...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009702(CHEMBL317398 | 2-Chloro-9-methyl-9H-purin-6-ylamin...)
Affinity DataIC50: 1.25E+6nMAssay Description:Inhibition of full length human C-terminal His-tagged Hsp90 alpha expressed in Escherichia coli by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50009702(CHEMBL317398 | 2-Chloro-9-methyl-9H-purin-6-ylamin...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity against adenosine A2 receptor in rat striatum by using [3H]NECA as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50009702(CHEMBL317398 | 2-Chloro-9-methyl-9H-purin-6-ylamin...)
Affinity DataKi:  1.60E+4nMAssay Description:Tested for inhibition of rat PC12 adenylate cyclase stimulation by using NECA as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50009702(CHEMBL317398 | 2-Chloro-9-methyl-9H-purin-6-ylamin...)
Affinity DataKi:  2.30E+4nMAssay Description:Binding affinity against adenosine A1 receptor in rat cortex by using [3H]- PIA as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed