BDBM50009619 CHEMBL91847::[1-(13-Cyclohexylmethyl-12-hydroxy-2,6,11-trioxo-1,7diaza-cyclotridec-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCC(=O)NCCCC(=O)[C@H](O)[C@H](CC2CCCCC2)NC1=O

InChI Key InChIKey=DYNAXOPFOQSIRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009619   

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009619(CHEMBL91847 | [1-(13-Cyclohexylmethyl-12-hydroxy-2...)
Affinity DataIC50: 1.40E+4nMpH: 7.4Assay Description:The compound was evaluated in vitro for inhibition of human plasma renin at pH 7.4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed