BDBM50009561 (E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol::2-Methoxy-5-[(E)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol::2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol::2-methoxy-5-(3,4,5-trimethoxystyryl)phenol::2-methoxy-5-[(E)-2-(3,4,5-trimethoxyphenyl)vinyl]phenol::CHEMBL36455::E-Combretastatin A-4::trans-2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol::trans-combretastatin A-4

SMILES COc1ccc(\C=C\c2cc(OC)c(OC)c(OC)c2)cc1O

InChI Key InChIKey=HVXBOLULGPECHP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50009561   

TargetTubulin beta-1 chain(Human)
University of Salford

Curated by ChEMBL
LigandPNGBDBM50009561((E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | 2...)
Affinity DataIC50: 5.00E+4nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009561((E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | 2...)
Affinity DataIC50: 680nMAssay Description:Inhibition of bovine brain tubulin polymerization incubated for 20 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
University of Salford

Curated by ChEMBL
LigandPNGBDBM50009561((E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | 2...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009561((E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | 2...)
Affinity DataIC50: 5.00E+4nMAssay Description:Ability to inhibit Tubulin polymerization in Bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2019
Entry Details Article
PubMed