BDBM50009530 3-(4-{2-[6-Amino-9-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-2-ylamino]-ethyl}-phenyl)-propionic acid::CHEMBL88070

SMILES Nc1nc(NCCc2ccc(CCC(O)=O)cc2)nc2n(cnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=PZXWQOIRBVHQTI-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009530   

TargetAdenosine receptor A1(Guinea pig)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50009530(CHEMBL88070 | 3-(4-{2-[6-Amino-9-(3,4-dihydroxy-5-...)
Affinity DataEC50:  1.12E+5nMAssay Description:Tested for adenosine A1 receptor agonistic activity by determining concentration needed to prolong the stimulus-QRS interval by 50% of the maximum re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50009530(CHEMBL88070 | 3-(4-{2-[6-Amino-9-(3,4-dihydroxy-5-...)
Affinity DataIC50: 1.26E+4nMAssay Description:Concentration required for 50% inhibition of [3H]-CHA binding on rat brain adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50009530(CHEMBL88070 | 3-(4-{2-[6-Amino-9-(3,4-dihydroxy-5-...)
Affinity DataIC50: 74nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed