BDBM50009185 4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carboxymethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid::CHEMBL296603::Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2

SMILES CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(O)=O

InChI Key InChIKey=FWGXLJYMZWCJJV-UHFFFAOYSA-N

Data  6 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50009185   

TargetMu-type opioid receptor(Guinea pig)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50009185(CHEMBL296603 | Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2 | ...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of opioid receptor mu in guinea pig ileum (GPI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50009185(CHEMBL296603 | Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2 | ...)
Affinity DataIC50: 184nMAssay Description:Opioid receptor binding affinity in rat brain membrane preparations by the displacement of [3H]- DPDPE (Opioid receptor delta 1-selective radioligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50009185(CHEMBL296603 | Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2 | ...)
Affinity DataIC50: 1.45E+4nMAssay Description:Displacement of [3H]- DAGO from opioid receptor mu in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50009185(CHEMBL296603 | Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2 | ...)
Affinity DataIC50: 5.60nMAssay Description:In vitro opioid receptor delta mediated mouse vas deferens (MVD) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50009185(CHEMBL296603 | Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2 | ...)
Affinity DataEC50:  0.331nMAssay Description:Negative logarithm of the molar concentration of delta receptor was determined in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50009185(CHEMBL296603 | Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2 | ...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity against opioid receptor delta in rats by displacing [3H]DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50009185(CHEMBL296603 | Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2 | ...)
Affinity DataKi:  0.310nMAssay Description:Inhibition of [3H]-DADLE binding to opioid receptor delta in P2 membrane preparation of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50009185(CHEMBL296603 | Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2 | ...)
Affinity DataKi:  0.410nMAssay Description:Compound was tested for its binding affinity against opioid receptor delta using [3H]DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50009185(CHEMBL296603 | Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2 | ...)
Affinity DataKi:  638nMAssay Description:Binding affinity against opioid receptor mu in rats by displacing [3H]-DAGOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50009185(CHEMBL296603 | Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2 | ...)
Affinity DataKi:  1.28E+3nMAssay Description:Inhibition of [3H]DAGO binding to trat brain opioid receptor mu in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50009185(CHEMBL296603 | Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2 | ...)
Affinity DataKi:  1.28E+3nMAssay Description:Inhibition of [3H]DAGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed