BDBM50009171 CHEMBL3238362

SMILES Cn1c(CN2C(=O)CN(C2=O)c2ccc(F)cc2)cc2cnc(nc12)C(=O)N[C@@H](CCCCN)C#N

InChI Key InChIKey=WTOFIEIGFUSGDJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50009171   

TargetPlasminogen(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50009171(CHEMBL3238362)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-LyspNA (S-2251) peptide as substrate assessed as reduction of enzyme hydrolytic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50009171(CHEMBL3238362)
Affinity DataIC50: 7.40E+5nMAssay Description:Inhibition of human plasma kallikerin using H-D-Phe-Pro-Arg-pNA (S-2302) peptide as substrate assessed as reduction of enzyme hydrolytic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50009171(CHEMBL3238362)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human plasma urokinase using Glu-Gly-Arg-pNA (S-2444) peptide as substrate assessed as reduction of enzyme hydrolytic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50009171(CHEMBL3238362)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of urokinase (unknown origin) using Pyr-Gly-Arg-MCA as substrate by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetPlasminogen(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50009171(CHEMBL3238362)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of plasmin (unknown origin) using Boc-Val-Leu-Lys-MCA as substrate by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed