BDBM50009155 CHEMBL3238310

SMILES CC#C[C@H]1CN(CCN1c1ncc(cn1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1

InChI Key InChIKey=CWDXIMHMPWZRFK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009155   

TargetGlucokinase regulatory protein(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50009155(CHEMBL3238310)
Affinity DataIC50: 10nMAssay Description:Inhibition of biotin-tagged human GKRP/fluorescein-tagged GK interaction preincubated for 20 mins prior to GK addition measured after 2 to 4 hrs by A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetGlucokinase regulatory protein(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50009155(CHEMBL3238310)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed