BDBM50009094 CHEMBL3237993

SMILES CC#C[C@H]1CN(CCN1c2ccc(cc2)S(=O)(=O)NC)S(=O)(=O)c3ccc(nc3)N

InChI Key InChIKey=AZCZVIWSFGSHOZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009094   

TargetGlucokinase regulatory protein(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50009094(CHEMBL3237993)
Affinity DataIC50: 35nMAssay Description:Inhibition of biotin-tagged human GKRP/fluorescein-tagged GK interaction preincubated for 20 mins prior to GK addition measured after 2 to 4 hrs by A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlucokinase regulatory protein(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50009094(CHEMBL3237993)
Affinity DataEC50:  97nMAssay Description:Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed