BDBM50009017 2-(4-Methyl-pyridin-3-ylmethyl)-1,2-dihydro-indazol-3-one::CHEMBL3144576

SMILES Cc1ccncc1Cn1[nH]c2ccccc2c1=O

InChI Key InChIKey=SAPSUQUIPZAYPE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009017   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009017(2-(4-Methyl-pyridin-3-ylmethyl)-1,2-dihydro-indazo...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009017(2-(4-Methyl-pyridin-3-ylmethyl)-1,2-dihydro-indazo...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009017(2-(4-Methyl-pyridin-3-ylmethyl)-1,2-dihydro-indazo...)
Affinity DataEC50:  2.08E+4nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed