BDBM50009016 2-(4-Phenyl-butyl)-1,2-dihydro-indazol-3-one::CHEMBL3144714

SMILES O=c1n(CCCCc2ccccc2)[nH]c2ccccc12

InChI Key InChIKey=VMGHZFARQGLROM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009016   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009016(2-(4-Phenyl-butyl)-1,2-dihydro-indazol-3-one | CHE...)
Affinity DataIC50: 780nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009016(2-(4-Phenyl-butyl)-1,2-dihydro-indazol-3-one | CHE...)
Affinity DataIC50: 2.60E+4nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009016(2-(4-Phenyl-butyl)-1,2-dihydro-indazol-3-one | CHE...)
Affinity DataEC50: >3.75E+5nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed