BDBM50008993 1-Benzyl-1,2-dihydro-indazol-3-one::CHEMBL8612

SMILES O=c1[nH]n(Cc2ccccc2)c2ccccc12

InChI Key InChIKey=SXPJFDSMKWLOAB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008993   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008993(CHEMBL8612 | 1-Benzyl-1,2-dihydro-indazol-3-one)
Affinity DataIC50: 3.40E+3nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008993(CHEMBL8612 | 1-Benzyl-1,2-dihydro-indazol-3-one)
Affinity DataEC50: >4.45E+5nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008993(CHEMBL8612 | 1-Benzyl-1,2-dihydro-indazol-3-one)
Affinity DataIC50: 3.10E+4nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed