BDBM50008974 2,3-Dimethyl-8-((E)-styryl)-imidazo[1,2-a]pyridine::2,3-Dimethyl-8-styryl-imidazo[1,2-a]pyridine::CHEMBL296417

SMILES Cc1nc2c(\C=C\c3ccccc3)cccn2c1C

InChI Key InChIKey=LOYDZPBTPYPEFJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008974   

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50008974(2,3-Dimethyl-8-styryl-imidazo[1,2-a]pyridine | CHE...)
Affinity DataIC50: 1.68E+3nMpH: 7.4Assay Description:Inhibition of purified H+/K+ ATPase at pH 7.4 as released inorganic phosphate from ATP using hog stomach gastric membrane vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50008974(2,3-Dimethyl-8-styryl-imidazo[1,2-a]pyridine | CHE...)
Affinity DataIC50: 990nMAssay Description:Inhibition of H+/K+ ATPase as reduced acid formation in rabbit gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed