BDBM50008967 (8-Benzyloxy-2,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-acetonitrile::CHEMBL43945

SMILES Cc1nc2c(OCc3ccccc3)c(C)ccn2c1CC#N

InChI Key InChIKey=PXCBXNJKWMCRNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008967   

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50008967(CHEMBL43945 | (8-Benzyloxy-2,7-dimethyl-imidazo[1,...)
Affinity DataIC50: 400nMAssay Description:Inhibition of H+/K+ ATPase as reduced acid formation in rabbit gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50008967(CHEMBL43945 | (8-Benzyloxy-2,7-dimethyl-imidazo[1,...)
Affinity DataIC50: 1.37E+4nMpH: 7.4Assay Description:Inhibition of purified H+/K+ ATPase at pH 7.4 as released inorganic phosphate from ATP using hog stomach gastric membrane vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed